Suitable for a first undergraduate course, the book includes all the basics necessary to prepare students for their future studies in mathematics, engineering, and the sciences. It presents the syntax from MATLAB, Maple, and to give students a better grasp of the theory and gain more insight into real-world problems. Along with covering traditional topics, the text describes a number of modern topics, such as direction fields, phase lines, the Runge-Kutta method, and epidemiological and ecological models. It also explains concepts from linear algebra so that students acquire a thorough understanding of differential equations.