This practical book describes the basic science, clinical presentation and management of the 67 common acute medical presentations stipulated in the Royal College of Physicians syllabus for Core Medical Training and Acute Core Common Stem. • Case scenarios are included for each presentation, and guidance about management is offered in the context of national guidelines and important studies. • Experienced clinicians describe their approach to common difficult problems and explain the answers to questions often asked on the ward round by successive generations of trainees. • Chapters highlight key decisions that need to be made early, common misunderstandings, and risks. • Detailed discussion provides an understanding of the rationale, allowing the reader to apply their knowledge to other situations. • Guidance is provided on urgency of referral, safe ambulatory management, and when to seek specialist help. This is an essential resource that provides readers with the knowledge base to practise as a confident medical registrar.