This book constitutes the refereed proceedings of the Second International Conference on Advanced Communication and Intelligent Systems, ICACIS 2023, held in Warsaw, Poland, during June 16–17, 2023 The 43 full papers included in this book were carefully reviewed and selected from 221 submissions. They were organized in topical sections as follows: Wireless Communication, Artificial Intelligence and Machine Learning, Robotics & Automation, Data Science, IoT and Smart Applications