The chapters, written by leading experts in their respective fields, are thematically divided into the following areas: prognostic studies and general epidemiology, pharmacovigilance, quality of life, survival analysis, clustering, safety and efficacy assessment, clinical design, models for the environment, genomic analysis, and animal health. This comprehensive volume will serve the health science community as well as practitioners, researchers, and graduate students in applied probability, statistics, and biostatistics.