A woman who sacrificed her shot at fame to focus on her family gets a second chance to live her dreams in this heartwarming comedy. Known to her friends as Miss E, Elestra Henton (Vanessa Bell Calloway) was a promising standup comedienne when she turned her back on the spotlight to save her marriage and raise her daughter. Years later, Miss E's marriage has failed, and she's estranged from her family. With nothing to fill the empty void at the center of her life, Miss E decides that the best cure for misery is laughter. She's determined to reclaim the career from the ruins, but in order to do so she'll first have to contend with her shady manager and ex-lover Buddy Felton (Roger Guenveur Smith), whose appearance back in her life sheds light on some long-suppressed family secrets.