Founded in 1531, the city was established as a Spanish settlement surrounded by important Indigenous towns. This situation prompted a colonial city that developed along Spanish colonial guidelines but became influenced by the native communities that settled in it, creating one of the most architecturally rich cities in colonial Spanish America, from the Renaissance to the Baroque periods. This book covers the city's historical background, investigating its civic and religious institutions as represented in selected architectural landmarks. Throughout the narrative, Burke weaves together sociological, anthropological, and historical analysis to discuss the city’s architectural and urban development. Written for academics, students, and researchers interested in architectural history, Latin American studies, and the Spanish American viceregal period, it will make an important contribution to the field.