In the late nineteenth century, increasing traffic of transpacific plants, insects, and peoples raised fears of a "biological yellow peril" when nursery stock and other agricultural products shipped from Japan to meet the growing demand for exotics in the United States. Over the next fifty years, these crossings transformed conceptions of race and migration, played a central role in the establishment of the US empire and its government agencies, and shaped the fields of horticulture, invasion biology, entomology, and plant pathology. In , Jeannie N. Shinozuka uncovers the emergence of biological nativism that fueled American imperialism and spurred anti-Asian racism that remains with us today. Shinozuka provides an eye-opening look at biotic exchanges that not only altered the lives of Japanese in America but transformed American society more broadly. She shows how the modern fixation on panic about foreign species created a linguistic and conceptual arsenal for anti-immigration movements that flourished in the early twentieth century. Xenophobia inspired concerns about biodiversity, prompting new categories of “native” and “invasive” species that defined groups as bio-invasions to be regulated—or annihilated. By highlighting these connections, Shinozuka shows us that this story cannot be told about humans alone—the plants and animals that crossed with them were central to Japanese American and Asian American history. The rise of economic entomology and plant pathology in concert with public health and anti-immigration movements demonstrate these entangled histories of xenophobia, racism, and species invasions.