Fernando Meirelles' adaptation of Nobel Prize-winning author Jos? Saramago's novel Blindness begins when an epidemic of blindness strikes the world. Mark Ruffalo stars as an eye doctor who awakens one morning to find that he suffers from the unexplained disorder. He, along with other victims, is sent to a government detention center so that they can be quarantined. His wife (Julianne Moore) pretends to be blind so that she can be with him inside the institution. Their time in the center grows more and more desperate as food and supplies dwindle, and one of the other citizens (Gael Garc?a Bernal) exercises dictatorial control over the others after he acquires a weapon.