This investigates the potential effects of the aqueous extract of large cardamom on hypertension and endothelium function in experimental models. Hypertension, a prevalent cardiovascular disorder, is associated with endothelial dysfunction, which plays a critical role in the progression of cardiovascular diseases. Large cardamom, a popular spice with reported medicinal properties, is believed to possess beneficial effects on various health conditions. The research employs experimental models to assess the impact of the aqueous extract of large cardamom on blood pressure levels and endothelial function. Through rigorous analysis and observation, the study aims to shed light on the extract's potential as a therapeutic agent for managing hypertension and improving endothelial health. The findings of this investigation could hold significant implications for healthcare, potentially paving the way for new approaches in managing hypertension and promoting cardiovascular well-being. As large cardamom is easily accessible and widely used in culinary practices, its potential health benefits warrant further exploration and validation.