The branch of medical science which focuses on the diagnosis and treatment of the ailments of the brain, the spinal cord and the peripheral nerves is known as clinical neurology. Biomarkers within this field are utilized for various purposes which include, determining the stage of a disease, guiding clinical diagnosis, monitoring progression or response to therapy, and assessing the risk associated with the disease. The biomarkers which are studied within the field of clinical neurology are found in the cerebral spinal fluid, and are not detectable in the blood. The blood brain barrier closely protects the brain and provides protection from various harmful substances present in the bloodstream. This barrier makes blood tests inconvenient and makes the brain's chemistry inaccessible. Latest advances used for detection through biomarkers, are making the brain accessible while making the neurological disorders treatable. This book explores all the important aspects of clinical neurology in the modern day. The readers would gain knowledge that would broaden their perspective about the importance of biomarkers within this field.