This proceedings constitutes the post-conference proceedings of the 3 EAI International Conference on Cognitive Computing and Cyber Physical Systems, IC4S 2022, held at Vishnu Institute of Technology, Bhimavaram in Andhra Pradesh, India, in November 26-27, 2022. The theme of IC4S 2022 was: . The 22 full papers were carefully reviewed and selected from 88 submissions. The papers are clustered in thematical issues as follows: machine learning and its applications; cyber security and networking; image processing; IoT applications; smart city eco-system and communications.