By providing the first multifaceted and holistic account of Pueblo settlements in the Rio Grande region over a period of 160 years, Barrett offers a new perspective on the dynamics of Pueblo-Spanish interactions. Spanish exploitation and disruption of the Pueblo economy, Apachean raids, and the impact of droughts are re-assessed. But a major epidemic from 1636-40 likely proved the most crucial factor in the reduction of Pueblo population and settlements. Moreover, the gradual realization of the extent of their losses and grasping what it would mean for their continued existence was probably the most important factor, more than religious or civil persecution, in galvanizing the Pueblo peoples to achieve the unprecedented unity that made possible their successful uprising in 1680. They were unable to sustain this unity when the Spanish returned in 1692 and suffered further losses of pueblos, population, and territory as a result of the reconquest. "No serious future work on the Pueblos can be undertaken without reference to this one. The text, simply put, clarifies the entire framework of early Spanish-Indian relations."—Marc Simmons