As it is used in this book, the term “cooperating robots” refers to robots that either cooperate with one another or with people. The book investigates various aspects of cooperation in the context of implementing flexible manufacturing systems. Accordingly, manufacturing systems are the main focus in the discussion on implementing such robotic systems. The book begins with a brief introduction to the concept of manufacturing systems, followed by a discussion of flexibility. Aspects of designing such systems, e.g. material flow, logistics, processing times, shop floor footprint, and design of flexible handling systems, are subsequently covered. In closing, the book addresses key issues in operating such systems, which concern e.g. decision-making, autonomy, cooperation, communication, task scheduling, motion generation, and distribution of control between different devices. Reviewing the state of the art and presenting the latest innovations, the book offers a valuable asset for a broad readership.