This interdisciplinary work reconstructs a conceptual web pervaded by various intellectual attitudes and drives. It presents an historical–epistemological unified itinerary which includes Copernicus, Kepler, Galileo, Descartes, Huygens, Newton and Leibniz. For each of the scientists and philosophers, a presentation and commentary is made of their cosmological views, and where relevant, outlines of their most relevant physical concepts are given. Furthermore, the authors highlight the philosophical and epistemological implications of their scientific works. This work is helpful both as a synthetic overview of early modern cosmology, and an analytical exposition of the elements that were intertwined in early-modern cosmology. This book addresses historians, philosophers, and scientists and can also be used as a research source book by post-graduate students in epistemology, history of science and history of philosophy.