Diabetes mellitus is one of the most common non-communicable metabolic disorders requiring prolonged dependence on medications. It can play havoc on multiple organ systems and demands precise control and expert management skills. Clinicians need to be knowledgeable, updated and highly alert while stepping into the realm of diabetic care. This handbook is a unique compilation of facts and concepts that are quintessential to practical management of diabetes in day-to-day clinical practice. It aspires to be of constant help as a reference guide to anyone in the field of medicine.