The themes of linearization, (re) integration, and global versus local calculus are emphasized throughout. Additional features include a treatment of the elements of multivariable calculus, formulated to adapt readily to the global context, an exploration of bundle theory, and a further (optional) development of Lie theory than is customary in textbooks at this level. New to the second edition is a detailed treatment of covering spaces and the fundamental group. Students, teachers and professionals in mathematics and mathematical physics should find this a most stimulating and useful text.