A teenage girl (Amandla Stenberg) is unable to leave her home because she has an immunodeficiency that makes her allergic to almost everything. However, her life changes for the better when she begins to communicate with the boy next door (Nick Robinson), and their relationship eventually inspires her to venture into the outside world. Everything, Everything was directed by Stella Meghie, and adapted from the YA novel of the same name by Nicola Yoon.