A dark and powerful creature threatens Gabriele's and Lilly's immortal existence, so Gabriele is forced to turn to Lucrezia, his maker. She reveals to him the horrors of her teenage years in the 16th Century in the house of the Borgias, and the possessive obsession of her brother, Caesare. Her transformation into a vampire gives her freedom, but leads her on a journey of discovery that shapes the events of the past, the present and the future. Does Lucrezia's strange past have something to do with Gabriele's and Lilly's problems in the present? What is the mysterious entity that seems to be stalking the vampires? Finding the answers is crucial to their survival.