The book is organised as follows: Chapter 1 presents the basic knowledge about fuzzy sets, genetic algorithms and neural nets necessary for a clear understanding of the rest of this book. Chapter 2 analyzes direct fuzzy inference based on fuzzy if-then rules. Chapter 3 is devoted to the tuning of fuzzy rules for direct inference using genetic algorithms and neural nets. Chapter 4 presents models and algorithms for extracting fuzzy rules from experimental data. Chapter 5 describes a method for solving fuzzy logic equations necessary for the inverse fuzzy inference in diagnostic systems. Chapters 6 and 7 are devoted to inverse fuzzy inference based on fuzzy relations and fuzzy rules. Chapter 8 presents a method for extracting fuzzy relations from data. All the algorithms presented in Chapters 2-8 are validated by computer experiments and illustrated by solving medical and technical forecasting and diagnosis problems. Finally, Chapter 9 includes applications of the proposed methodology in dynamic and inventory control systems, prediction of results of football games, decision making in road accident investigations, project management and reliability analysis.