Genetic toxicology is recognized by geneticists and researchers concerned with the genetic impact of man-made chemicals. In , expert researchers in the field provide comprehensive genetic toxicology prools. These include in vitro and in vivo prools on mutation assays, cytogenetic techniques, and primary DNA damage, assays in alternate to animal models, and updated ICH guidelines. Written in the highly successful series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory prools, as well as key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, seeks to aid research students and scientists working in regulatory toxicology as well as biomedical, biochemical and pharmaceutical sciences.