Handbook of Engineering Management: The Digital Economy focuses on multidisciplinary integration and complex evolving systems. It discusses the incorporation of a system of systems along with engineering economic strategies for sustainable economic growth. This handbook highlights functional leadership as the main part of an engineering manager’s competency and discusses how to form alliances strategically. In addition, it presents a comprehensive guide for the implementation of an environmental management system and shows how environmental and social impacts can be assessed in an organization applying digital tools. This handbook also brings together the three important areas of Engineering Management: Knowledge Management, the Digital Economy, and Digital Manufacturing. In addition, this handbook provides a comprehensive guide to implementing an environmental management system and shows how environmental and social impacts in an organization can be assessed using digital tools. Based on the authors’ practical experience, it describes various management approaches and explains how such a system can be used to prioritize actions and resources, increase efficiency, minimize costs, and lead to better, more informed decision making. It is essential to follow a systematic approach and to ask the right questions, whether the system is managed and implemented by humans, AI, or a combination of both. This handbook is laid out in a series of simple steps and dispels the jargon and myths surrounding this important management tool. This handbook is an ideal read for engineering managers, project managers, industrial and systems engineers, supply chain engineers, professionals who want to advance their knowledge, and graduate students.