In this issue of , guest editors Drs. Olga Pozdnyakova and Carlo Brugnara bring their considerable expertise to the topic of . Top experts in the field discuss how automation may be applied to hematology, coagulation, and flow cytometry; novel technologies for routine hematology and coagulation analysis to enhance readers’ knowledge of new digital technologies used for cell analysis and classification in hematology; and new uses of flow cytometry in the diagnosis of hematological malignancies, red cell disorders, and platelet function alterations.