This book constitutes the refereed proceedings of the 4th EAI International Conference on Industrial Networks and Intelligent Systems, INISCOM 2018, held in Da Nang, Vietnam, in August 2018. The 26 full papers were selected from 38 submissions and are organized thematically in tracks: Telecommunications Systems and Networks; Industrial Networks and Applications; Hardware and Software Design and Development; Information Processing and Data Analysis; Signal Processing; Security and Privacy.