This book presents new ideas, analysis, implementations and evaluation of the next generation intelligent techniques for solving complex decision problems in large-scale distributed systems. In 15 chapters several important formulations of the decision problems in heterogeneous environments are identified and a review of the recent approaches, from game theoretical models and computational intelligent techniques, such as genetic, memetic and evolutionary algorithms, to intelligent multi-agent systems and networking are presented. We believe that this volume will serve as a reference for the students, researchers and industry practitioners working in or are interested in joining interdisciplinary works in the areas of intelligent decision systems using emergent distributed computing paradigms. It will also allow newcomers to grasp key concerns and potential solutions on the selected topics.