Chuck Marshall has the stand-up comedy world in the palm of his hand - big-time gigs, streaming specials and his own network TV show. Then he mysteriously disappears. Duckie Dunne, Chuck's original comedy partner, sets out to locate his old friend. To help his search, Duckie enlists the aid of Cheryl, daughter of the late comedy legend Mickey Gross. However, Mickey may not be quite as dead as everyone thinks. Duckie and Cheryl's path take them from the deserts of Arizona to the forests of British Columbia. Along the way, they encounter a slippery Buddhist monk, a megalomaniac network executive and a psycho self-help guru. At the end of their long, strange trip is a secret comics' retreat and an explosive comedy showdown!