This essential handbook provides specific and concise instructions for creating new technologies, building innovation, obtaining funding, protecting ideas, and much more. It includes detailed outlines of SBIR/STTR grants, business plans, operating agreements, investor presentations, research studies, and FDA regulatory pathways, thereby saving tremendous time and effort for scientific innovators and technology entrepreneurs. This comprehensive guide also presents a clear framework for navigating the complexities of patents, finance, grants, venture capital, private equity, regulatory compliance, technology creation, and many other aspects. With several tips and tricks for succeeding on a minimal budget, this work covers crucial steps from beginning to end, including: Registering a company, business plan outlines, accelerators & incubators, grant writing & opportunities, SBIR/STTR grant instructions, federal research programs & resources, angel financing, venture capital funding, investor pitches, equity considerations, additional funding methods, intellectual property protection, patent writing, partnership & licensing agreements, non-disclosure agreements, regulatory approval & compliance, clinical studies & outlines, FDA approval pathways, guidance for drugs, devices, and biologics, investigational device & 510(k) outlines, market analysis & strategy, legal considerations, healthcare reimbursement, exit strategies, & much more!