In healthcare: health monitoring systems for heart patients, a model for cardiovascular disease prediction, early diabetic detection, COVID-19 screening from cough sound, and detection in epidemiological diseases. In natural language processing: summarization of major Arabic machine translation corpora, impact of normalization, and data augmentation on named entity recognition (NER) task on Algerian text. In Agriculture 5.0: schedule of the most widely used IoT architectures and plant recognition. In robotics: visually real-time control of a mobile EV3 robot in an indoor environment. In social media: the identification of rumors on social networks. In computer vision and biometrics: illumination-robust face recognition system. In IoT ecosystem, networks and cloud computing: technologies and prools, architectures and modeling IoT applications, Named Data Networking (NDN) for the emergent IoT, unmanned aerial vehicle carried base stations (UAV-BSs) placement problem in 5G networks, assignment of the submitted tasks to the available resources in a cloud computing environment, providing routes in the presence of obstacles, and security aspects. Finally, the reader finds how to approach problems even if they have no algorithmic or no exact solution by using the following techniques developed in the different chapters of this book: deep CNN models and dense CNN models, voluntary simulation, hybrid gray wolf optimizer (GWO), multi-verse optimizer (MVO), coronavirus herd immunity optimizer (CHIO) algorithm, multi-population differential evolution, graphical formalism with machine learning and Color Petri Nets, and extension of BPMN 2.0.