This book has its objective to explore the readiness of distance education students for online learning. A descriptive research design was employed for this empirical study. A multistage sampling procedure was used to select three regions in Ghana and six study centers from the regions out of which 306 first-year students enrolled in distance education programs at the University of Cape Coast participated in the study. Data were analyzed by using descriptive statistics specifically mean and standard deviation as well as inferential statistics thus independent sample t-test and standard multiple linear regression. The study revealed that students possessed good self-regulated learning and collaborative skills necessary for online learning. The author recommended that the management of Universities running distance education programs especially in sub-Saharan Africa should direct their focus to the formulation of appropriate and operational distance education policies to guide the college students towards successful implementation of online learning since their target audience (students) have a positive attitude toward online learning.