Researchers, students, and engineers in computer science, big data, applied mathematics, operations research, algorithm design, artificial intelligence, software engineering, data analysis, industrial and systems engineering will benefit from the state-of-the-art results presented in modern graph theory and its applications to the design of efficient algorithms for optimization problems. Topics covered in this work include: · Graphs where maximal cliques and stable sets intersect · The maximum independent set problem with special classes · A general technique for heuristic algorithms for optimization problems · The network design problem with cut constraints · Algorithms for computing the frustration index of a signed graph · A heuristic approach for studying the patrol problem on a graph · Structural and algorithmic results on branchings in digraphs · Improved upper bounds for Korkel—Ghosh benchmark SPLP instances