The conference, attended by eightyfive mathematicians from eleven countries, was organized by the Stefan Banach International Mathematical Center. This volume contains articles from leading experts in the world on cryptography and computational number theory, providing an account of the state of research in a wide variety of topics related to the conference theme. It is dedicated to the memory of the Polish mathematicians Marian Rejewski (1905-1980), Jerzy Róøycki (1909-1942) and Henryk Zygalski (1907-1978), who deciphered the military version of the famous Enigma in December 1932 – January 1933. A noteworthy feature of the volume is a foreword written by Andrew Odlyzko on the progress in cryptography from Enigma time until now.