The geographical position of Brazil and Colombia, their shared border problems and their operational affinity could represent the possibility of regional military cooperation, since they share common interests, such as protecting the Amazon, and both countries lack multi-engine vectors in their air forces that can be complemented through international agreements. This paper analyzes the feasibility of such cooperation, through bibliographical and documentary research and technical-operational analysis, and seeks to verify the possibility and format of bilateral military cooperation between the Colombian Air Force (FAC) and the Brazilian Air Force (FAB), for the protection of the Amazon, using the KC-390 aircraft. The results, based on documentary research and a literature review, point to the viability of bilateral cooperation along the lines of the European Air Transport & Air-to-Air Refueling (Atares) model, in which the Brazilian KC-390 complements the FAC and the Colombian KC-767s increase the training of Brazilian FAB pilots.