Conducting empirical studies at a university in Beijing, involving 400 pre-service teachers, the author investigates factors influencing pre-service teachers’ practical knowledge. Five innovative methodologies, namely concept mapping, visual metaphors, video analysis, epistemic network analysis, and formative interventions are employed to make pre-service teachers’ practical knowledge visible, helping to increase our theoretical understanding of practical knowledge and proposing practical guidelines for the reorganisation of initial teacher education. While the study is grounded in mainland China, the methodological thinking and theoretical discussions can inspire international scholars and teacher educators, and therefore contribute to the global reform of teacher education.