The essays in this volume explore how the region has become a complex arena of political, cultural, and economic contestation between actors that include the state, environmental groups and NGOs, and private businesses and how local actors are reconfiguring their subjectivities and political agency in response. With its multinational perspective, and its examination of major themes including missionization, millenarian movements, the Chaco war, industrial enclaves, extractivism, political mobilization, and the struggle for rights, this volume brings greater visibility to an underrepresented, complex region.