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Role of Capsaicin in Oxidative Stress and Cancer / Edition 1
Barnes and Noble
Role of Capsaicin in Oxidative Stress and Cancer / Edition 1
Current price: $109.99
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Barnes and Noble
Role of Capsaicin in Oxidative Stress and Cancer / Edition 1
Current price: $109.99
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This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cyhrome P-450 in the bioactivation; identification of mihondria as the key target site for oxidative stress; involvement of mihondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival pathways including PI3K/Akt and the involvement of intrinsic mihondrial cell death pathway.