Taking a break from their usual business of helping adoptees find their birth parents, New York private investigators - and super-sized, ever-so-slightly-paranormal siblings - Fran and Ken Stein accept a job to find a missing young woman. Nineteen-year-old college student Eliza Hennessey is trans - and she has a rocky relationship with her father, their new client. Brian's convinced his daughter's vanished, rather than run away, but Fran and Ken aren't so sure she wants to be found. The PI duo investigate, and soon Fran is butting heads with her irritating sort-of-ex-boyfriend Mank at the NYPD, who has what seems to be a similar case on his desk. But not even Fran could guess how tangled their investigations are going to get, and how deep they'll need to dive into murder and mayhem to solve the case!