This book is about science in theatre and performance. It explores how theatre and performance engage with emerging scientific themes from artificial intelligence to genetics and climate change. The book covers a wide range of performance forms from Broadway musicals to educational theatre, from Somali drama to grime videos. It features work by pioneering companies including Gob Squad, Headlong Theatre and Theatre of Debate as well as offering fresh analysis of global blockbusters such as Wicked and Urinetown. The book offers detailed description and analysis of theatre and performance practices as well as broader commentary on the politics of theatre as public engagement with science. Science in performance is essential reading for researchers, students and practitioners working between science and the arts within fields such as theatre and performance studies, science communication, interdisciplinary arts and health humanities.