Recent advances in wireless communication technologies have enabled the large-scale deployment of next-generation wireless networks, and many other wireless applications are emerging. The next generation of mobile networks continues to transform the way people communicate and access information. As a matter of fact, next-generation emerging networks are exploiting their numerous applications in both military and civil fields. For most applications, it is important to guarantee high security of the deployed network in order to defend against attacks from adversaries, as well as the privacy intrusion. The key target in the development of next-generation wireless networks is to promote the integration of the human, cyber, and physical worlds. Previous work in Cyber Physical Systems (CPS) considered the connection between the cyber world and the physical world. In the recent studies, human involvement brings new channels and initiatives in this interconnection. In this integration process, security and privacy are critical issues to many wireless network applications, and it is a paramount concern for the growth of next-generation wireless networks. This is due to the open nature of wireless communication and the involvement of humans. New opportunities for tackling these security and privacy issues in next-generation wireless networks will be achieved by leveraging the properties of interaction among human, computers and things.