This book is specifically devoted to the study of evolution equations – i.e., of time-dependent differential equations such as the heat equation, the wave equation, or the Schrödinger equation (quantum graphs) – bearing in mind that the majority of the literature in the last ten years on the subject of differential equations of graphs has beendevoted to elliptic equations and related spectral problems. Moreover, for tackling the most general settings - e.g. encoded in the transmission conditions in the network nodes - one classical and elegant tool is that of operator semigroups. This book is simultaneously a very concise introduction to this theory and a handbook on its applications to differential equations on networks. With a more interdisciplinary readership in mind, full proofs of mathematical statements have been frequently omitted in favor of keeping the text as concise, fluid and self-contained as possible. In addition, a brief chapter devoted to the field of neurodynamics of the brain cortex provides a concrete link to ongoing applied research.