A youthful Sherlock Holmes is recuperating from the ordeal destined to be chronicled by Dr. Watson as A Study in Scarlet. Holmes' next adventure, the lost adventure, starts mundanely enough with the theft of a typewriter but for one outré fact: The death of the beautiful supplicant's manservant. More thefts and purloined documents carry Holmes and Watson across Europe on the Orient Express in search of the truth. A devilishly clever cipher and a murdered sailor lead Holmes to a horrifying conclusion. Travel with the great detective and Dr. Watson from the steaming jungles of the Sundra Strait to long forgotten caverns beneath London to face a new arch villain, Lofcadio Hearseborne III, and the greatest terror of their lives.