At Baker Street, Sherlock Holmes is in turmoil since the news brought by Scotland Yard: the great novelist Ames Douglas has been poisoned! Everything seems to indicate suicide, but a note with a coded message persuades the famous detective to the contrary ... Step into the shoes of Dr. Watson and lead the investigation alongside Sherlock Holmes: decide what to look for, pick up the clues and discover the meaning of this coded message, which will lead to the culprit! Sherlock Holmes is a comic combined with a game dubbed "The comic in which you are the hero". You embody a character in a immersive story in which your choices guide your progress. You have a character sheet akin to those used in role-playing games that tracks your possessions, your special abilities, your coins, and your victory points. In general, gameplay consists in following the comic's panels — which contain clues, riddles and traps — and making choices about where to go and what to do, while using your visual perception to collect clues and be smart enough to resolve the riddles.