This book provides a multidisciplinary view of smart infrastructure through a range of diverse introductory and advanced topics. The book features an array of subjects that include: smart cities and infrastructure, e-healthcare, emergency and disaster management, Internet of Vehicles, supply chain management, eGovernance, and high performance computing. The book is divided into five parts: Smart Transportation, Smart Healthcare, Miscellaneous Applications, Big Data and High Performance Computing, and Internet of Things (IoT). Contributions are from academics, researchers, and industry professionals around the world. • Features a broad mix of topics related to smart infrastructure and smart applications, particularly high performance computing, big data, and artificial intelligence; • Includes a strong emphasis on methodological aspects of infrastructure, technology and application development; • Presents a substantial overview of research and development on key economic sectors including healthcare and transportation.