This book covers various topics, including the choice of materials and techniques for assembling responsive membranes with ability to transport mass, energy and signals on demand; the reader will find through the book an extensive description of the best techniques used to monitor molecular scale events, which are regarded as responsible for the smartness of multifunctional objects and for the conversion of chemical signals into optical, electrical, thermal and mechanical responses. The reader is encouraged to use this cross-disciplinary discussion for his own research. Chemical, biological and physical concepts, expressed through the book, contribute to form a common language, which will allow the reader to discover causes for reflection and innovation, measuring how smart objects with desired properties can be tailored from exiting materials and used flexibly for different developed applications. Specifically: The potential of sensor-like membranes in some key strategic fields is examined with particular emphasis on biomedicine, food and textiles markets. The benefits arising from the use of smart membranes are analysed in terms of life quality, safety, and innovation.