This book examines issues across the lifespan of transgender and nonbinary individuals whilst synthesizing conceptual work, empirical evidence, pedagogical content, educational experiences, and the voices of transgender and nonbinary individuals. It highlights the resilience and resistance of transgender and nonbinary individuals and communities to challenge narratives relying on one-dimensional perspectives of risk and tragic lives. While there is currently unprecedented visibility and increasing support, members of these communities still face shockingly high rates of violence, victimization, unemployment, discrimination, and family rejection. Significant need for services and support coupled with social, clinical, and medical service systems ill-equipped to provide culturally responsive care illustrates the critical need for quality education and training of educators, practitioners, and service providers in best practices of working with members of the transgender and nonbinary community. Organized into six sections: this book offers a current, comprehensive, and intersectional guide for students, practitioners, and researchers across a variety of professions, including social work, psychology, public policy, and health care.