focuses on the advancement of basic and applied research related to plant-microbe interaction and their implementation in progressive agricultural sustainability. The book also highlights the developing area of bioinformatics tools for the interpretation of metabolome, the integration of statistical and bioinformatics tools to manage huge generating data, metabolite profiling, and key signaling-driven substances, along with a section on the role of key biosynthetic pathways. Focused on selecting positive and effective interactive core-microbiome which will be adaptive and sustainable, this book will help researchers further improve the quality and productivity of crops through sustainable agriculture.