Worldwide, boys are 50 percent less likely than girls to meet basic proficiency in reading, math, and science. ADHD is on the rise. And as boys become young men, their suicide rates go from equal to girls to six times that of young women. Boys are growing up with less-involved fathers and are more likely to drop out of school, drink, do drugs, become delinquent, and end up in prison. Boys' old sense of purpose—being a warrior, a leader, or a sole breadwinner—are fading. Many bright boys are experiencing a "purpose void," feeling alienated, withdrawn, and addicted to immediate gratification. A comprehensive blueprint for what parents, teachers, and policymakers can do to help our sons become happier, healthier men, and fathers and leaders worthy of our respect.