While at a casino to celebrate her birthday, Jess Clarke proposes a pact to her reserved sister, Liz, and their childhood friend Chloe: the three women will say yes to any adventure that comes their way. Jess is mourning her recent divorce, so the other two reluctantly agree. Twelve hours later, they awaken to the shocking consequences of their behavior. A viral video throws Liz’s career and reputation into question. A major loss at the craps table rocks the foundation of Chloe’s staid marriage. And Jess’s desperate bid to unblock her artistic creativity results in a life-changing choice. Staring down the crossroads, each woman finds her relationships—with herself, with each other, and with loves both old and new—tested. At every turn, they struggle not to let fear decide their fates. Will they give in, or will their misadventures lead to the greatest fulfillment of all?