Though antiracism is a critical, emerging topic, it has received limited attention in the literature. Its focus is the eradication of racism while delivering justice and emancipation. This collection advances the concept by highlighting ways that research, theory, and practice are shifting the conversation to dismantling and eliminating racism. It shows how racism has traumatized marginalized individuals, limited their participation in the workforce and society, and hindered their psychological well-being. This Handbook is divided into 4 sections: the historical foundations of racism; knowledge derived from research, theory, and lived experiences; practical application of antiracism in educational and workplace settings; and the future of antiracism research. Coming at a time of racial unrest and much discourse on race, this work provides scholars, professionals, and students with a body of research and practical examples that introduces and informs them on the concept of antiracism in HRD. Though the focus is on the US, the arguments put forth in this handbook are not localized, they are universal and can be applied in multiple contexts.