In 2020, some higher education leaders successfully navigated the unprecedented challenges the year presented and emerged as resilient agents of change in their academic communities. Freeman A. Hrabowski III was one of many leaders who followed the science during the pandemic and followed his heart in the fight for racial justice, even though the science was often playing catch-up with the virus, and campuses were playing catch-up on the history of race in our country. This precarious position often left higher education leaders in the disquieting position of making decisions with only partial or changing information. Drawing from lessons learned in real scenarios, the authors provide practical recommendations for empowering colleagues, cultivating resilience and courage, and sustaining purpose and inclusion within institutions. Building on Hrabowski's previous book , offers university leaders invaluable insight into how the qualities of openness, resilience, courage, passion, and hope can be harnessed in times of crisis to guide their institutions to thrive.