Have you ever wondered how we age and why we get sick? the third book in a trilogy that includes and exposes the chronic inflammatory underworld and how it does its dirty business to transform end organ interstitial spaces into a sea of diseases. The book clarifies how this transition is evoked, how it disables the signaling apparatus of the protective capillary cells, and then proceeds to dismantle all of the cells within the interstitial space that capillaries are friendly to. In the end, after mission accomplished, the interstitial space footprint now belongs to chronic inflammation and the anti-organ. In this final apocalypse, capillary cells have long since stopped dancing, and their feedback loop signals to the allied partners have been replaced by rogue influences. White blood cells, cytokines, platelets, and immunoglobulins within the darkened corners of end organ interstitial spaces now belong to chronic inflammation. The interstitial spaces becomes barren and lifeless as we no it. A perfect backdrop for disease venues, pain, fatigue and aging. It is not too long afterword, that the end organ takes a slit to the throat.