An important and comprehensive review of an expanding research area. The book will combine all classical knowledge in the field with recent advances to provide a full and comprehensive coverage of the field. Transcription factors are important in regulating gene expression, and their analysis is of paramount interest to molecular biologists studying this area. This book looks at the basic machinery of the cell involved in transcription in eukaryotes, the factors involved in transcription and progresses to look at the regulatory systems which control this machinery both within the cell and also in the wider systems of the mammalian organism.